Karen Redmond, consultant thoracic and lung transplant surgeon and her team at the Mater Misericordiae University Hospital in Dublin have broken new ground by carrying out a new type of lung transplant procedure called ex vivo lung perfusion transplantation (EVLP). This procedure makes donor lungs previously classed as unsuitable safe for transplant.
Up until now more than 80 percent of donated lungs could not be transplanted into recipients. This has meant substantial waiting lists for those needing a lung transplant. Reasons for this include the damage to the lungs caused by a donor illness or the presence of the donors white blood cells in a transplanted lung which may increase the likelihood of the lung being rejected. During EVLP the lungs are maintained at normal body temperature and perfused with a bloodless fluid known as Steen solution, which contains high levels of albumin, dextran and an electrolyte composition. This process helps to reverse lung injury and remove excess lung water and donor white cells.
Ms Redmond and the Mater team are predicting that while the procedure is still in its infancy it is hoped that for every two organ donors currently deemed unsuitable for lung transplant, using EVLP can restore the lungs of one. This will significantly increase the size of the current donor pool.
Karen Redmond spoke at our patient conference last October and gave an excellent synopsis on lung transplant in Ireland and as well as discussing this new procedure.
For more about organ donation and transplant in Ireland click here.
Info Centre
WhatisAlpha-1Antitrypsin?
Alpha-1 antitrypsin is a vital protein produced by the liver to protect the lungs. It provides protection from the harmful effects of infections and inhaled irritants, particularly tobacco smoke. It can be easily measured by a simple blood test.
WhatisAlpha-1AntitrypsinDeficiency?
Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which, after cystic fibrosis, is the commonest genetic disorder in Ireland. It severely affects more than 15,000 people, with another 250,000 carriers also at risk of lung and liver disease on the island of Ireland. It is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD).
HowDoIGetTested?
The Alpha-1 Foundation Ireland provides free testing for Alpha-1 as part of a national screening programme which is funded by the HSE. It is a simple blood test. For more details ring 01-8093871 or email alpha1@rcsi.ie
New Lung Transplant Procedure
Karen Redmond, consultant thoracic and lung transplant surgeon and her team at the Mater Misericordiae University Hospital in Dublin have broken new ground by carrying out a new type of lung transplant procedure called ex vivo lung perfusion transplantation (EVLP). This procedure makes donor lungs previously classed as unsuitable safe for transplant.
Up until now more than 80 percent of donated lungs could not be transplanted into recipients. This has meant substantial waiting lists for those needing a lung transplant. Reasons for this include the damage to the lungs caused by a donor illness or the presence of the donors white blood cells in a transplanted lung which may increase the likelihood of the lung being rejected. During EVLP the lungs are maintained at normal body temperature and perfused with a bloodless fluid known as Steen solution, which contains high levels of albumin, dextran and an electrolyte composition. This process helps to reverse lung injury and remove excess lung water and donor white cells.
Ms Redmond and the Mater team are predicting that while the procedure is still in its infancy it is hoped that for every two organ donors currently deemed unsuitable for lung transplant, using EVLP can restore the lungs of one. This will significantly increase the size of the current donor pool.
Karen Redmond spoke at our patient conference last October and gave an excellent synopsis on lung transplant in Ireland and as well as discussing this new procedure.
For more about organ donation and transplant in Ireland click here.
Info Centre
What is Alpha-1 Antitrypsin?
Alpha-1 antitrypsin is a vital protein produced by the liver to protect the lungs. It provides protection from the harmful effects of infections and inhaled irritants, particularly tobacco smoke. It can be easily measured by a simple blood test.
What is Alpha-1 Antitrypsin Deficiency?
Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which, after cystic fibrosis, is the commonest genetic disorder in Ireland. It severely affects more than 15,000 people, with another 250,000 carriers also at risk of lung and liver disease on the island of Ireland. It is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD).
How Do I Get Tested?
The Alpha-1 Foundation Ireland provides free testing for Alpha-1 as part of a national screening programme which is funded by the HSE. It is a simple blood test. For more details ring 01-8093871 or email alpha1@rcsi.ie