What is Alpha-1 Antitrypsin?

Alpha-1 antitrypsin is a vital protein produced by the liver to protect the lungs. It provides protection from the harmful effects of infections and inhaled irritants, particularly tobacco smoke. It can be easily measured by a simple blood test.

What is Alpha-1 Antitrypsin Deficiency?

Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which can cause lung, liver, and skin disease. It severely affects more than 15,000 people, with another 250,000 carriers also at risk on the island of Ireland. Alpha-1 most often leads to chronic obstructive pulmonary disease (COPD) and people with Alpha-1 should avoid smoking at all costs.

How Do I Get Tested?

Alpha-1 Foundation Ireland provides free testing for Alpha-1 as part of a national detection programme which is funded by the HSE. For more details ring 01-8093871 or email alpha1@rcsi.ie.

Who are we?

Alpha-1 Foundation Ireland was founded in 2001 and is based in the RCSI Education and Research Centre at Beaumont Hospital. We are dedicated to raising awareness, increasing diagnosis, promoting research, and improving the treatment of Alpha-1. Our vision is that every person with Alpha-1 in Ireland is diagnosed and receives specialist care and treatment in a timely fashion.