How Do I Get Tested?

June 10, 2014 Alpha1 Admin Comments Off

There are 2 tests required to correctly diagnose alpha-1 antitrypsin deficiency.

The first test is called an alpha-1 antitrypsin (AAT) level, the second more informative test is called an AAT phenotype. An AAT level measures how much AAT protein is in the blood. However, a low AAT level does not provide a definitive diagnosis because AAT can be increased if you are sick or feeling unwell. The definitive test to diagnose AAT deficiency is called an AAT phenotype test.

Importantly, if you have a family history of AAT deficiency, talk to your family doctor and ask for both AAT level and AAT phenotype. Alpha-1 Foundation Ireland provide the test for free as part of a HSE-funded national targeted detection programme.

Other groups recommended for AAT deficiency testing include those with:

COPD (regardless of age or smoking history)
Severe asthma that does not respond to usual medications
Liver disease of unknown cause
A skin condition called panniculitis
Vasculitis
A low blood AAT level

For further details on how to get tested for Alpha-1 please contact:

Alpha-1 Foundation Ireland, RCSI Education & Research Centre, Beaumont Hospital, Dublin 9.

Phone: 01-8093871 or 01-8093749

Email: alpha1@rcsi.ie

Info Centre

What is Alpha-1 Antitrypsin?

Alpha-1 antitrypsin is a vital protein produced by the liver to protect the lungs. It provides protection from the harmful effects of infections and inhaled irritants, particularly tobacco smoke. It can be easily measured by a simple blood test.

What is Alpha-1 Antitrypsin Deficiency?

Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which, after cystic fibrosis, is the commonest genetic disorder in Ireland. It severely affects more than 15,000 people, with another 250,000 carriers also at risk of lung and liver disease on the island of Ireland. It is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD).

How Do I Get Tested?

The Alpha-1 Foundation Ireland provides free testing for Alpha-1 as part of a national screening programme which is funded by the HSE. It is a simple blood test. For more details ring 01-8093871 or email alpha1@rcsi.ie