Researchers from the Alpha One Foundation, the Royal College of Surgeons in Ireland and Harvard University have made a major breakthrough in identifying people who have an increased risk of developing COPD (chronic

The Irish Times, the Irish Examiner, the RTE website, the Evening Herald and several other newspapers have this week (January 13th) reported a new discovery by scientists based at the Royal College of

Irish scientists based at Beaumont Hospital have been involved in a multicentre study to determine the first ever international standard for alpha-1 antitrypsin. This study will make it easier for research groups and

A new study which was presented at the Irish Thoracic Society annual scientific meeting for 2008 held in Belfast in November highlighted the high prevalence of Alpha-1 in Ireland. (more…)

Researchers from the Department of Medicine at RCSI Beaumont Hospital attended the American Thoracic Society Annual Conference 2008 recently to present some of their findings in the area of Alpha-1. (more…)

Researchers in the Department of Medicine at RCSI Beaumont Hospital have been awarded a prestigious European award to study cells of the immune system from people with alpha-1 antitrypsin deficiency (Alpha-1).European Alpha-1-Antitrypsin Laurell’s

Monday, 24 November 2008 12:41 Health Research Board (HRB)/Medical Research Charities Group (MRCG) Project Description: Current treatments for AAT deficiency are based on augmentation therapy with recombinant or plasma-purified AAT and focus almost

Monday, 24 November 2008 12:25 Poster presentations DA Bergin, Greene CM, Taggart CC, O’Neill SJ and McElvaney NG. Activation of the EGFR by Human Neutrophil Elastase. Royal College of Surgeons in Ireland Research

We recently undertook a research project to identify the incidence of AATD in a representative sample of the general population of Ireland. This involved screening 1000 anonymised DNA samples for the presence of

Alpha-1 antitrypsin (AAT) is an antiprotease produced chiefly by the liver. Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder characterised by low serum levels of AAT and is associated with lung and liver