In May 2016 the HSE designated the Alpha One Foundation at Beaumont Hospital as the National Centre of Expertise for Alpha-1.

The Alpha One Foundation is based in the RCSI Education & Research Centre at Beaumont Hospital in Dublin. Alpha One Foundation staff of 4 includes a CEO who is also an experienced respiratory nurse specialist, a dedicated senior laboratory scientist, a clinical research associate and a specialist Alpha-1 nurse. These positions are supported through funding from the Department of Health and Children and the Health Service Executive (HSE).   

The Alpha One Foundation hosts an information centre for members of the public and healthcare professionals and enquiries can be made by phone or email. The national referral centre for Alpha-1 is based at Beaumont Hospital in Dublin. Here, the rapid access specialist Alpha-1 clinic is available for newly-diagnosed Alphas where they are seen by a multidisciplinary team including doctors, nurses, respiratory scientists, and physiotherapists. Professor N.G. McElvaney supervises the Alpha-1 clinic at Beaumont Hospital and is a consultant respiratory physician with over 30 years experience of Alpha-1. 

AOF activities

Figure 1. Alpha One Foundation Activities

What is Alpha-1 Antitrypsin?
Alpha-1 antitrypsin is a vital protein produced by the liver to protect the lungs. It provides protection from the harmful effects of infections and inhaled irritants, particularly tobacco smoke. It can be easily measured by a simple blood test. 
What is Alpha-1 Antitrypsin Deficiency?
Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which, after cystic fibrosis, is the commonest genetic disorder in Ireland. It severely affects more than 15,000 people, with another 250,000 carriers also at risk of lung and liver disease on the island of Ireland. It is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD).
How Do I Get Tested?
The Alpha One Foundation provides free testing for Alpha-1 as part of a national screening programme which is funded by the HSE. For more details ring 01-8093871 or email